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PET/CT和MRI在多发性骨髓瘤中的应用与进展
引用本文:陈建普,李崇佼,文兵,何勇.PET/CT和MRI在多发性骨髓瘤中的应用与进展[J].国际放射医学核医学杂志,2018,42(5):447-452.
作者姓名:陈建普  李崇佼  文兵  何勇
作者单位:430071, 武汉大学中南医院核医学科
摘    要:多发性骨髓瘤(MM)是一种恶性B细胞肿瘤,其主要累及骨髓,部分也可出现髓外浸润。影像学检查是全面评估MM不可或缺的手段,X射线与CT对病灶的检出率低、定量能力差。PET/CT与MRI对MM的评估具有较大的价值,特别是18F-FDG及其他新型分子探针,全身扩散加权成像、动态增强MRI及水脂分离等MRI新技术。笔者就PET/CT及MRI在MM中的应用与进展进行综述。

关 键 词:多发性骨髓瘤    磁共振成像    正电子发射断层显像计算机体层摄影术    全身扩散加权成像
收稿时间:2018-02-22

The application and progress of PET/CT and MRI in multiple myeloma
Jianpu Chen,Chongjiao Li,Bing Wen,Yong He.The application and progress of PET/CT and MRI in multiple myeloma[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,42(5):447-452.
Authors:Jianpu Chen  Chongjiao Li  Bing Wen  Yong He
Institution:Department of Nuclear Medicine, Zhong Nan Hospital of Wuhan University, Wuhan 430071, China
Abstract:Multiple myeloma (MM) is a malignant B-cell neoplasm, primarily involving the bone marrow, and some may have extramedullary involvement. Imaging examination is an indispensable tool for comprehensive assessment of MM X-ray and CT have lower lesion detection rate, poor quantitative ability. PET/CT and MRI have great value in the assessment of MM, especially the application of 18F-FDG and other novel molecular probes, whole-body diffusion weighted imaging (DWI), dynamic contrast-enhanced (DCE) MRI and water-fat separation. The author will review the application and progress of PET/CT and MRI in MM.
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