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Determining the Survival Rate of Colorectal Cancer in Iran: A Systematic Review and Meta-Analysis
Authors:Bahram Tahmasbi1Ghasem Abedi1Mahmood Moosazadeh1Ghasem Janbabai2Fereshteh Farshidi1Kamyar Mansori3   4Yousef Moradi5Fatemeh Khosravi Shadmani6Serveh Parang7Zaher Khazaei8
Abstract:Objective: Colorectal cancer is one of the most common causes of death in the world. Despite of remarkableadvances in medical sciences, cancer is an important disease and the second cause of death after cardiovascular diseases.The present study was aimed at determining the survival rate of colorectal cancer in Iran. Methods: The present studyis a systematic review of national and international electronic databases. Studies that had the inclusion criteria wereincluded in the study, electronically published articles over December 2007 and March 2015 were retrieved. The collecteddata were analyzed by meta-analytic method through stata 11.0 Software, and the survival rate was measured. Results:The 1-, 2-, 3-, 4-, and 5-year survival rates of colorectal cancer in Iran were respectively calculated as 85, 75.10, 65,55.40, and 52.The results indicated that there is a significant relationship between anatomic location of tumor andsurvival rate. According to the results of this examination, survival rate of the patients with rectal cancer was 41.9times higher than those with colorectal cancer. Conclusion: Due to the relative high prevalence of this cancer amongyoung people in Iran and the low survival rate, early diagnosis of colorectal neoplasms is necessary before they becomesymptomatic through more effective diagnosis programs of enhancing the patients’ health and survival rate. Moreover,it is necessary to conduct more specialized and relevant studies in order to determine genetic or environmental causes ofcancer such as diet and cultural and behavioral habits at the national level and with different ethnicities.
Keywords:Keywords: colorectal cancer   survival rate  meta- analysis  Iran
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