口服固体制剂精准分剂量在精准用药中的探索与实践

目的:为医院口服固体制剂的使用提供一种精准分剂量方法,为临床合理用药提供参考。方法:利用药片切割器、药片磨粉器等对口服固体制剂进行分劈、磨粉或胶囊内容物直接分装,并称重进行调整,以保证分剂量准确度控制在均分量的85%~115%以内。结果:提供药品精准分剂量服务,能够保证分剂量准确度,提高用药安全性、有效性和方便性,减少药品浪费,降低用药成本。结论:医院药学部门开展药品精准分剂量是精准用药的现实基础,使医院药学服务更加精细,提高患者用药依从性,医护患满意,值得推广。

The exploration and practice of precision minute dose of solid preparations in precision medication

OBJECTIVE To provide a method for precision minute dose administration of solid preparations in hospital, and a reference for clinical reasonable application of drugs. METHODS Solid preparations was split by tablet-cutter or tablet-pulverizer, weighed and adjusted to guarantee the weight of minute dose in the average weight of 85%-115%. RESULTS Solid preparations split accurately could guarantee precision drug doses, improve drug safety, efficacy and convenience, decrease drug cost and waste while ensuring patient accessibility to treatment. CONCLUSION Hospital pharmacy department should use minute dose of solid preparations as the basis of precision medication, provide more individualized hospital pharmacy services, and improve patient compliance and satisfaction. Doctors, nurses and patients are satisfied with this medication mode, which is worthy of promotion.