体质量指数对青少年24 h眼压波动的影响

目的　探讨体质量指数（body mass index，BMI）对青少年24 h眼压波动的影响。方法　本研究共纳入90名健康青少年。采用Goldmann压平式眼压计测量受试者24 h眼压波动（5∶00 am、7∶00 am、10∶00 am、2∶00 pm、6∶00 pm、10∶00 pm）。BMI通过体质量（kg）除以身高（m）的平方计算。根据BMI将受试者分为低体质量及正常组（BMI<25 kg·m^-2）50人，超重组（25 kg·m^-2≤BMI<30 kg·m^-2）22人和肥胖组（BMI≥30 kg·m^-2）18人。使用SPSS 22.0统计软件对测量值进行统计学分析。结果　所有观察对象平均眼压、眼压峰值、眼压谷值和眼压波动值分别为（16.72±3.30）mmHg（1 kPa=7.5 mmHg）、（19.26±3.68）mmHg、（14.29±3.26）mmHg和（4.98±1.91）mmHg。3组间眼压波动值差异比较无统计学意义（均为P＞0.05）。低体质量及正常组与肥胖组间平均眼压、眼压峰值和眼压谷值差异比较有统计学意义（均为P＜0.05），而低体质量及正常组与超重组、超重组与肥胖组差异比较无统计学意义（均为P＞0.05）。Pearson相关分析结果显示，BMI与平均眼压、眼压峰值呈显著正相关（P＜0.05）。结论　在青少年人群中，BMI较高者具有更高的平均眼压、眼压峰值。

Effects of body mass index on 24-hour intraocular pressure fluctuations in adolescences

Objective　To investigate the effects of body mass index (BMI) on 24-hour intraocular pressure (IOP) fluctuations in adolescences.Methods　Totally 90 healthy adolescences were included in the study.Measurements of 24-hour IOP were obtained by Goldmann applanation tonometer on 5∶00 am，7∶00 am，10∶00 am，2∶00 pm，6∶00 pm and 10∶00 pm.BMI was calculated as weight in kilograms divided by the square of height in meters (kg·m^-2).The patients were divided into three groups according to BMI，and they were Group 1 (BMI＜25 kg·m^-2)，Group 2 (25≤BMI＜30 kg·m^-2)，Group 3 (BMI≥30 kg·m^-2).Data were analyzed by statistic software SPSS 22.0.Results　The mean of IOP，peak IOP，valley IOP and fluctuation value of IOP were (16.72±3.30)mmHg (1 kPa=7.5 mmHg)，(19.26±3.68)mmHg，(14.29±3.26)mmHg and (4.98±1.91)mmHg，respectively.And there was no significant differences in the fluctuation value of IOP among the three groups (all P>0.05)；the differences in mean IOP，peak IOP，valley IOP between group 1 and group 3 were significant (all P<0.05).However，the differences between group 1 and group 2，group 2 and group 3 showed no significant differences (all P>0.05).Pearson correlation analysis showed that BMI was positively correlated with mean IOP and peak IOP (both P<0.05).Conclusion　In the adolescent population，individuals with higher BMI tend to have higher mean IOP and peak IOP.