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The Effect of Gluten Free Diet on Components of Metabolic Syndrome: A Randomized Clinical Trial
Authors:Mehdi Ehteshami1Rahebeh Shakerhosseini1Fatemeh Sedaghat2Mehdi Hedayati3Hassan Eini-Zinab4Azita Hekmatdoost1
Abstract:Background: This study aimed to assess the effects of Gluten free diet (GFD) on components of metabolic syndrome(MES). Materials and Methods: In this randomized clinical trial, 50 subjects diagnosed with MES were randomlydivided into two groups (n=25). The first group received a GFD and the second group continued their regular diet.Biochemical markers of MES and blood pressure were measured before and after 8-week intervention. Results: Fortyfive subjects completed the study. A post-hoc comparison of the groups showed no effects of the GFD and controldiet on LDL cholesterol, total cholesterol, fasting insulin, HOMA-IR, systolic and diastolic blood pressure levels. TheGFD reduced fasting blood glucose, waist circumference (WC) and serum triglyceride concentration significantlycompared with the control diet (p<0.05). Conclusion: Short-term GFD reduced WC and improved glycemic controland Triglyceride level in subjects with the metabolic syndrome.
Keywords:Gluten free diet  Metabolic Syndrome  Obesity
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