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Different microbiological and clinical aspects of lower respiratory tract infections between China and European/American countries
Authors:Xin Zhang  Rui Wang  Xiuzhen Di  Bin Liu  Youning Liu
Affiliation:1.Department of Respiratory Diseases, 2.Department of Clinical Pharmacology, Chinese PLA General Hospital, Beijing 100853, China
Abstract:

Background

National treatment/diagnosis guidelines for lower respiratory tract infections (LRTIs) are generally based on local epidemiological data. Etiology and drug-resistance patterns could differ between China and European/American countries, and simply following their respective guidelines might cause problems in clinical practice. Therefore, we need to summarize the microbiology and clinical manifestations of LRTIs in China and develop our own guidelines.

Methods

Three major national multicenter epidemiology surveillance studies on LRTI were completed recently. The data were compared in detail with those from European/American studies.

Results

Clinical and microbiological differences were observed in community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), and pulmonary mycosis between our country and European/American countries.

Conclusions

The microbiological and clinical characteristics of the major LRTIs in China differ in many respects from those in European/American countries. Patients should have personal treatment plans instead of simply following the guidelines from foreign countries
Keywords:Pathogens   epidemiology   antimicrobial resistance   lower respiratory tract infections (LRTIs)
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