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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers |
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| Authors: | Gregory R Hoffman Rami Rahal Frank Buxton Kay Xiang Gregory McAllister Elizabeth Frias Linda Bagdasarian Janina Huber Alicia Lindeman Dongshu Chen Rodrigo Romero Nadire Ramadan Tanushree Phadke Kristy Haas Mariela Jaskelioff Boris G Wilson Matthew J Meyer Veronica Saenz-Vash Huili Zhai Vic E Myer Jeffery A Porter Nicholas Keen Margaret E McLaughlin Craig Mickanin Charles W M Roberts Frank Stegmeier Zainab Jagani |
| Institution: | Departments of aDevelopmental and Molecular Pathways and;bOncology, Novartis Institutes for BioMedical Research, Cambridge, MA, 02139;;cOncology Translational Medicine, Novartis Pharma, Cambridge, MA, 02139; and;dDepartment of Pediatric Oncology, Dana–Farber Cancer Institute, Boston, MA, 02215 |
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