| 中药防治疲劳作用机制的研究进展 |
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| 引用本文： | 杨言言,李惠珍,艾志福,宋永贵,陈丽玲,刘亚丽,杨明,朱根华,苏丹. 中药防治疲劳作用机制的研究进展[J]. 中草药, 2023, 54(7): 2309-2318 |
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| 作者姓名： | 杨言言 李惠珍 艾志福 宋永贵 陈丽玲 刘亚丽 杨明 朱根华 苏丹 |
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| 作者单位： | 江西中医药大学中医药防治认知障碍脑疾病江西省重点实验室, 江西 南昌 330004;江西中医药大学 抑郁症中医证候动物模型、中药药效（防治精神障碍脑疾病）评价江西省中医药管理局重点研究室, 江西 南昌 330004;南昌医学院药效与安全性评价江西省卫生健康委员会重点实验室, 江西 南昌 330004;江西中医药大学中医药防治认知障碍脑疾病江西省重点实验室, 江西 南昌 330004;江西古香今韵大健康产业有限公司, 江西南昌 330004 |
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| 基金项目： | 国家中医药多学科交叉创新团队项目（中医药创新团队及人才支持计划）：中药研制与中药安全性创新团队（ZYYCXTD-D-202207）；江西中医药大学校级科技创新团队发展计划（CXTD22008）；江西省教育厅科技计划（GJJ218915，GJJ201206，GJJ201239） |
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| 摘 要： | 疲劳是亚健康的典型表现，会导致身体发生一系列的生理变化。长期疲劳如不及时缓解，可诱发心血管功能障碍、精神障碍等严重病理反应。中药为防治疲劳、减缓继发性疾病提供了可靠的临床实践，具有抗疲劳作用的天然药物种类丰富，为开发利用新型抗疲劳药物提供崭新领域。通过对疲劳的认识、中药与天然药物防治疲劳的复杂机制进行综述，为揭示中药干预疲劳提供理论依据，也为开发具有抗疲劳潜力的新产品提供指导。
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| 关 键 词： | 中药 抗疲劳 线粒体能量代谢 神经保护 内分泌调节 抗氧化活性 |
| 收稿时间： | 2022-10-24 |
Research progress on mechanism of traditional Chinese medicine in prevention and treatment of fatigue |
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| YANG Yan-yan,LI Hui-zhen,AI Zhi-fu,SONG Yong-gui,CHEN Li-ling,LIU Ya-li,YANG Ming,ZHU Gen-hu,SU Dan. Research progress on mechanism of traditional Chinese medicine in prevention and treatment of fatigue[J]. Chinese Traditional and Herbal Drugs, 2023, 54(7): 2309-2318 |
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| Authors: | YANG Yan-yan LI Hui-zhen AI Zhi-fu SONG Yong-gui CHEN Li-ling LIU Ya-li YANG Ming ZHU Gen-hu SU Dan |
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| Affiliation: | Key Laboratory of TCM for Prevention and Treatment of Brain Diseases with Cognitive Dysfunction, Jiangxi University of Chinese Medicine, Nanchang 330004, China;Key Laboratory of Depression Animal Model Based on TCM syndrome, Key Laboratory of Evaluation of Traditional Chinese Medicine Efficacy (Prevention and Treatment of Brain Disease with Mental Disorders), Nanchang 330004, China;Key Laboratory of Efficacy and Safety Evaluation, Health Commission of Jiangxi Province, Nanchang Medical College, Nanchang 330004, China;Key Laboratory of TCM for Prevention and Treatment of Brain Diseases with Cognitive Dysfunction, Jiangxi University of Chinese Medicine, Nanchang 330004, China;Jiangxi Guxiang Jinyun Comprehensive Health Industry Co., Ltd., Nanchang 330004, China |
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| Abstract: | Fatigue is a typical manifestation of sub-health, which will lead to a series of physiological changes in the body. If long-term fatigue is not relieved in time, it can induce serious pathological reactions such as cardiovascular dysfunction and mental disorders. Traditional Chinese medicine provides reliable clinical practice for preventing fatigue and alleviating secondary diseases. Natural drugs with anti-fatigue effects are rich in variety and resources which provides a new field for the development of new anti-fatigue drugs. Through the review of the understanding of fatigue and the complex mechanism of traditional Chinese medicine and natural medicine in preventing fatigue, which provides theoretical basis for revealing the intervention of traditional Chinese medicine in fatigue, and also provides guidance for developing new products with anti-fatigue potential. |
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| Keywords: | traditional Chinese medicine anti-fatigue mitochondrial energy metabolism neuroprotection endocrine regulation antioxidant activity |
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