Disturbed sleep in bipolar disorder is related to an elevation of IL-6 in peripheral monocytes |
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| Authors: | Philipp S. Ritter Karsten Kretschmer Andrea Pfennig Bettina Soltmann |
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| Affiliation: | 1. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitatsklinikum Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany;2. DFG-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Cluster of Excellence, Fetscherstraße 105, 01307 Dresden, Germany |
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| Abstract: | Bipolar disorder is a severe psychiatric disorder that is associated with persistent changes in the quality, duration and architecture of sleep. Currently there is no unifying hypothesis explaining the alterations in sleep observable in patients with bipolar disorder and management is often difficult though vital. |
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| Keywords: | IL, interleukin TNF, tumor necrosis factor IFN, interferon CNS, central nervous system TGF, transforming growth factor NREM, non-rapid eye movement sleep REM, rapid eye movement sleep |
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