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Assessment of linear-scale indices for perimetry in terms of progression in early glaucoma
Authors:Gardiner Stuart K  Demirel Shaban  Johnson Chris A  Swanson William H
Affiliation:a Discoveries in Sight Laboratories, Devers Eye Institute, Legacy Health, Portland, OR, USA
b Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA
c School of Optometry, Indiana University, Bloomington, IN, USA
Abstract:Currently, global indices that summarize the visual field combine sensitivities on a logarithmic (decibel) scale. Recent structure-function models for glaucoma suggest that contrast sensitivity should be converted to a linear scale before averaging across visual field locations, to better relate sensitivity with the number of surviving retinal ganglion cells (RGCs). New indices designed to represent the number of RGCs already lost are described. At least one was found to be a significantly better predictor of subsequent rate of change than traditional Mean Deviation (p = 0.014) in participants with glaucomatous optic neuropathy. Issues concerning the creation of optimal global indices are discussed.
Keywords:Glaucoma   Perimetry   Quantification   Visual field   Progression
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