| 超声心动图监测淋巴瘤患者蒽环类药物化疗后右心室亚临床功能减退的应用 |
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| 引用本文： | 宋飞艳,.超声心动图监测淋巴瘤患者蒽环类药物化疗后右心室亚临床功能减退的应用[J].复旦学报(医学版),2016,43(2):231. |
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| 作者姓名： | 宋飞艳 |
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| 作者单位： | 1 复旦大学附属中山医院心脏超声诊断科 上海 200032；2 上海市心血管病研究所 上海 200032；3 上海市影像医学研究所 上海 200032 |
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| 基金项目： | 国家自然科学基金 (81201095) |
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| 摘 要： | 蒽环类药物显著提高了淋巴瘤患者的生存率,但其心脏毒性不容忽视。近年来,随着临床上对右心室的关注度提高,蒽环类药物对右心室功能的损害成为研究热点。目前常用于监测蒽环类药物心脏毒性的检查手段有生物学标志物、心电图、心脏磁共振、心内膜活检术、超声心动图等。本文就上述检查手段特别是超声心动图新技术,如组织多普勒显像、应变/应变率显像、斑点追踪超声心动图、实时三维超声心动图等，监测淋巴瘤患者蒽环类药物化疗后右心室亚临床功能减退的应用现状作一综述。
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| 关 键 词： | 蒽环类 淋巴瘤 右心室功能障碍 超声心动图 |
| 收稿时间： | 2015-04-14 |
Application of echocardiography for subclinical dysfunction of right ventricle induced by anthracycline in patients with lymphoma |
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| SONG Fei-yan,,CHENG Lei-lei,.Application of echocardiography for subclinical dysfunction of right ventricle induced by anthracycline in patients with lymphoma[J].Fudan University Journal of Medical Sciences,2016,43(2):231. |
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| Authors: | SONG Fei-yan CHENG Lei-lei |
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| Institution: | 1 Department of Echocardiography,Zhongshan Hospital,Fudan University,Shanghai 200032,China; 2 Shanghai Institute of Cardiovascular Disease,Shanghai 200032,China; 3 Shanghai Institute of Medical Imaging,Shanghai 200032,China |
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| Abstract: | Anthracycline provides considerable therapeutic benefit in most patients with lymphoma.However,the cardiotoxicity of anthracycline in these patients cannot be ignored.In recent years,with the right ventricular function being given attention gradually,subclinical dysfunction of right ventricle induced by anthracycline has attracted worldwide attention.This review was concentrated on various methods of detecting the subclinical cardiotoxicity of anthracycline on right ventricle in patients with lymphoma,such as biological markers,electrocardiogram,cardiac magnetic resonance,endocardial biopsy and echocardiography. The novel echocardiographic technique including tissue Doppler imaging,strain and strain rate imaging,speckle tracking echocardiography and real-time 3-dimensional echocardiography were involved in detail. |
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| Keywords: | anthracyclines lymphoma right ventricular dysfunction echocardiography |
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