| 高雄激素血症-胰岛素抵抗-黑棘皮病综合征1例 |
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| 引用本文： | 刘玉峰,樊建勇,夏汝山,沈柱,党育平,胡绍文. 高雄激素血症-胰岛素抵抗-黑棘皮病综合征1例[J]. 临床皮肤科杂志, 2005, 34(6): 378-379 |
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| 作者姓名： | 刘玉峰 樊建勇 夏汝山 沈柱 党育平 胡绍文 |
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| 作者单位： | 第四军医大学西京医院皮肤科,陕西,西安,710032;第四军医大学西京医院内分泌科,陕西,西安,710032 |
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| 摘 要： | 报告1例高雄激素血症-胰岛素抵抗-黑棘皮病综合征，患者女，14岁。8岁开始肥胖，12岁初潮，1年后停经，唇上部，驱干，四肢毳毛增多，颈部，腋窝，腹股沟等处皮肤色素沉着，呈天鹅绒样增厚。皮损有典型的组织病理改变，血清胰岛素，睾酮水平升高。给予二年双胍治疗3个月后，病情好转。
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| 关 键 词： | 高雄激素血症-胰岛素抵抗-黑棘皮病综合征 |
| 文章编号： | 1000-4963(2005)06-0378-02 |
| 修稿时间： | 2004-09-21 |
A case of hyperandrogenism, insulin resistance and acanthosis nigricans syndrome |
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| LIU Yu-feng,FAN Jian-yong,XIA Ru-shan,SHEN Zhu,DANG Yu-ping,HU Shao-wen. A case of hyperandrogenism, insulin resistance and acanthosis nigricans syndrome[J]. Journal of Clinical Dermatology, 2005, 34(6): 378-379 |
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| Authors: | LIU Yu-feng FAN Jian-yong XIA Ru-shan SHEN Zhu DANG Yu-ping HU Shao-wen |
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| Abstract: | A case of 14-year-old female with hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome is reported. The patient became obesity when she was 8 years old. Her menarche was at the age of 12 years with menolipsis one year later. Physical examination showed the hyperpigmentation and the papillary hypertrophy on the neck, axillae, and groins with the hypertrichosis on the up lip, trunk and limbs. Skin biopsy showed a typical characteristic of acanthosis nigricans. Serum insulin and testosterone level were elevated. After the treatment of metformin for 3 months, patient's condition was improved. |
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| Keywords: | hyperandrogenism insulin resistance acanthosis nigricans syndrome |
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