急性重症脑血管病亚低温治疗的分析

目的:分析急性重症脑血管病(SCD)亚低温治疗的临床疗效。方法:选取60例SCD患者,随机分为2组,各30例,研究组应用SDLV型双控局部颅脑降温仪实施亚低温治疗;对照组采取常规治疗;比较2组患者临床疗效。结果:研究组恢复良好率明显高于对照组(46.67%vs 23.33%,P0.05);病死率明显低于对照组(20.00%vs43.33%,P0.05)。治疗后研究组内皮素(ET)、精氨酸加压素(AVP)、丙二醛(MDA)、血清一氧化氮(NO)等指标改善均明显优于对照组(均P0.05)。研究组血清L-选择素(L-selectin)、细胞间粘附分子-1(ICAM-1)水平明显优于对照组(均P0.05)。治疗后研究组神经功能缺损评分(ESS)、日常生活能力Bathel指数评分(BI)、运动功能评分(FMA)、生活质量评分(QOL评分)改善均明显优于对照组(均P0.05)。结论:亚低温治疗SCD患者,可促进神经功能恢复,改善患者预后,降低病死率,提高患者生活质量。

Severe acute cerebrovascular disease and the analysis of the cryogenic treatment

objective: to analysis the clinical curative effect of acute severe cerebrovascular disease and the low temperature treatment. Methods: to select 2010 04 04, 2015 in our hospital treated 30 cases of acute severe cerebrovascular disease as a team, the implementation of the low temperature treatment; In the same period from 30 cases as control group in patients with acute severe cerebrovascular disease adopt regular treatment; Compared two groups of patients with clinical efficacy. Results: the team good recovery rate was significantly higher than the control group 46.67% 23.33%; Mortality was 20.00% less than 43.33% of the control group obviously; The difference was statistically significant (P < 0.05). Group after treatment, ET indicators improved, AVP, MDA, NO, etc were significantly better than the control group, the difference was statistically significant (P < 0.05).