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HPLC法测定阿苯达唑颗粒的含量
引用本文:邵超.HPLC法测定阿苯达唑颗粒的含量[J].黑龙江医药,2011,24(3):341-342.
作者姓名:邵超
作者单位:安徽省阜阳市食品药品检验所,阜阳,236015
摘    要:目的:建立阿苯达唑颗粒含量的高效液相测定方法.方法:色谱柱为Waters C18 柱(4.6mmx150mm,5μm),流动相为甲醇一水(75:25),流速为1.0ml/min,检测波长为295nm,柱温为30℃.结果:阿苯达唑在1- 20μg/ml浓度范围内呈良好线性关系(r=1.0),平均加样回收率为100.1%(...

关 键 词:高效液相色谱法  含量测定  阿苯达唑颗粒

Content Determination of Albendazole Granules by HPLC
Shao Chao.Content Determination of Albendazole Granules by HPLC[J].Heilongjiang Medicine,2011,24(3):341-342.
Authors:Shao Chao
Institution:Shao Chao Anhui Fuyang Institute for Food and Drug Control(Fuyang 236015)
Abstract:Objective:To establish a HPLC method for determining of Albendazole Granules.Methods:Waters CI8 column(4.6 mm x 150 mm,5μm)was used with a mobile phase composed of methanol-water(80:20)at the flow rate of 1.0ml/min,the detection wavelength was 295 nm and the temperature of the column was 30℃.Results:The calibration curve of Albendazole was linear in the range of 1-20μg/ml,r=1.0.the average recovery rate Was 100.1% with a RSD of 0.21%(n =5).Conclusion:This method is accurate,realiable and can be used for the of determining Albendazole Granules.
Keywords:HPLC  Determination  Albendazole Granules
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