Ameloblastic carcinoma, secondary type: a case report |
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Authors: | Karakida Kazunari Aoki Takayuki Sakamoto Haruo Takahashi Miho Akamatsu Tadashi Ogura Go Sekido Yasutomo Ota Yoshihide |
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Institution: | Department of Oral and Maxillofacial Surgery, Tokai University Hachioji Hospital, Tokyo, Japan. karakida@is.icc.u-tokai.ac.jp |
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Abstract: | Malignant variants of ameloblastoma include metastasizing ameloblastoma, which microscopically appears benign but has metastasized and ameloblastic carcinoma that exhibits malignant histopathologic features. Ameloblastic carcinoma is classified into 2 types: a primary odontogenic malignancy and a secondary type resulting from malignant transformation of ameloblastoma. Most secondary ameloblastic carcinomas result from malignant transformation of a primary lesion after repeated postsurgical recurrences. Therefore it is rare to find an untreated secondary type presenting with histologic features of malignant transformation from an earlier benign lesion. We experienced a rare case of ameloblastic carcinoma, secondary type which might arise in an untreated ameloblastoma. The mechanism by which a preexisting benign ameloblastoma goes through a malignant transformation is also described. |
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