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Synthesis and biological evaluation of delavayin-C
Authors:Shinde Nirmala V  Himaja M  Bhosale S K  Ramana M V  Sakarkar D M
Affiliation:Department of Pharmaceutical Chemistry, N. G. S. M. Institute of Pharmaceutical Sciences, Nanthoor, Mangalore-575 005, India
Abstract:The synthesis of a cyclic heptapeptide, delavayin-C, cyclo(gly-tyr-tyr-tyr-pro-val-pro) is described. The structure of this compound was established on the basis of analytical IR, (1)H NMR and FAB mass spectral data. The antibacterial and antifungal activities of this peptide are also described.
Keywords:Cyclic peptide   delavayin-C   antibacterial   antifungal   p-nitrophenylester method
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