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Antibacterial Activity of Barringtonia acutangula against Selected Urinary Tract Pathogens
Authors:Sahoo S  Panda P K  Mishra S R  Parida R K  Ellaiah P  Dash S K
Affiliation:University Department of Pharmaceutical Sciences, Utkal University, Bhubaneswar-751 004, India;1Pharmaceutical Biotechnological Division, Department of Pharmaceutical Sciences, Andhra University, Visakhapatanam-530 003, India;2P. G. Department of Microbiology, Orissa University of Agriculture and Technology, Bhubaneswar-751 003, India
Abstract:Barringtonia acutangula (L.) Gaertn belonging to family Barringtoniaceae was investigated to evaluate In vitro antibacterial activity of aqueous, ethanolic, petroleum ether and chloroform extracts against Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Enterococcus faecalis and Escherichia coli the major urinary tract infection causing pathogens were tested by disc diffusion assay method and the minimum inhibitory concentration was evaluated. Ethanol (95%) extract exhibited broader spectrum of inhibition followed by chloroform, petroleum ether and aqueous extracts against the urinary tract pathogens under test. An attempt has been made to compare the activity of extracts with standard antibiotics against selected urinary tract infection causing pathogens.
Keywords:Barringtonia acutangula   antibacterial activity   UTI pathogens   minimum inhibitory concentration
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