Short-Term Synaptic Plasticity in the Visual Cortex During Development

The maturation of short-term synaptic plasticity was studiedin slices of the visual cortex obtained from rats during thefIrst 47 days of postnatal life. Responses of cortical neuronsto repetitive stimulation of the white matter at frequencies>5 Hz were examined by recording intracellularly at the restingmembrane potential level. Paired-pulse facilitation, an increasein the excitatory intracellular response following an initialresponse, was present in