Pseudomembranous colitis associated with chemotherapy with 5-fluorouracil |
| |
Authors: | Rafael Morales Chamorro Raquel Serrano Blanch María José Méndez Vidal María Auxiliadora Gómez España María Jesús Rubio Pérez Juan Rafael de la Haba Rodríguez Enrique Aranda Aguilar |
| |
Institution: | Servicio de Oncología Médica, Hospital Universitario Reina Sofía, Córdoba, Spain. romancordoba@hotmail.com |
| |
Abstract: | Pseudomembranous colitis is frequently associated with antibiotics and more rarely with chemotherapeutic agents such as 5-fluorouracil. The objective of this study is to show that it is possible to confuse this infection with chemotherapy associated toxicity. We present a 54 year old woman who underwent surgery for colorectal cancer and in the first cycle of chemotherapy with 5-fluorouracil developed pseudomembranous colitis. We detected the toxin B of Clostridium difficile in stools and we began early antibiotic treatment. Thus, in patients with post chemotherapy neutropenia and diarrhoea that develop negatively, we have to rule out this infection. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |