| 乌鸡白凤丸调脂作用研究 |
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| 引用本文： | 严玉平,王鑫国,牛丽颖,白霞,郭秋红.乌鸡白凤丸调脂作用研究[J].中药药理与临床,2003,19(6):6-8. |
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| 作者姓名： | 严玉平 王鑫国 牛丽颖 白霞 郭秋红 |
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| 作者单位： | 河北医科大学中医学院,石家庄,050091 |
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| 摘 要： | 目的：探讨乌鸡白凤丸的调脂作用。方法：采用去卵巢的方法及高脂饲料喂养法复制高血脂大鼠模型，观察血脂、脂蛋白、脂质过氧化物、肝脏系数等指标变化。结果：乌鸡白凤丸可明显降低大鼠甘油三脂(TG)、氧化低密度脂蛋白(OX—LDL)、丙二醛(MDA)和肝脏系数，升高高密度脂蛋白(HDL-C)、载脂蛋白AI(apo-AI)、超氧化物歧化酶(SOD)活力。结论：乌鸡白凤丸有明显调脂作用。
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| 关 键 词： | 乌鸡白凤丸 调脂作用 中药 药理 |
Study on the adjustability of Wujibaifeng Pill(乌鸡白凤丸)in hyperlipidemia rat |
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| Yan Yuping,Wang Xinguo,Niu Liying,Bai Xia,Guo Qiuhong.Study on the adjustability of Wujibaifeng Pill(乌鸡白凤丸)in hyperlipidemia rat[J].Pharmacology and Clinics of Chinese Materia Medica,2003,19(6):6-8. |
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| Authors: | Yan Yuping Wang Xinguo Niu Liying Bai Xia Guo Qiuhong |
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| Abstract: | Objective: To study the adjustability of Wujibaifeng Pill to rat's dyslipidemia. Methods: To observe the varieties of serum lipids, lipoprotein cholesterol, superoxide dismutase (SOD) and liver proportion of dyslipoproteinemia rats which acused by ovariotomy or feeding with superfatted forage. Results: It proved that the Wujibaifeng Pill could lower serum oxidized-low density lipoprotein cholesterol (OX-LDL, P<0.01), triglyceride (TG, P<0.01 or P<0.05), malondialdehyde (MDA, P<0.01 or P<0.05) and liver proportion, it could simultaneity enhance serum high desity lipoprotein cholesterol (HDL-C, P<0.01 or P<0.05), apolipoprotein AI (apo-AI, P<0.01) and SOD activities (P<0.01). Conclusion: It suggested that Wujibaifeng Pill could markedly prevent rats from dyslipidemia. |
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