帕洛诺司琼预防肺癌化疗中恶心、呕吐的效果观察

目的:探析帕洛诺司琼预防肺癌化疗中恶心、呕吐的效果。方法:随机选择晚期肺癌化疗患者40例,分为观察组与对照组。观察患者化疗中急性呕吐反应、延迟呕吐的情况、恶心分级情况及改善不良反应。结果:观察组患者急性呕吐与对照组差异无统计学意义(P>0.05);延迟呕吐情况、患者恶心控制情况,观察组均显著高于对照组。观察组不良反应发生率较对照组低,差异无统计学意义(P>0.05)。结论:晚期肺癌的化疗中,帕洛诺司琼在延迟呕吐的止吐方面及患者恶心控制方面较阿扎司琼疗效好,在急性呕吐止吐方面作用与阿扎司琼相似,临床不良反应轻微,值得推广应用。

Explore the effect of palonosetron prevent nausea and vomiting in lung cancer chemotherapy

Objective To explore the effect of palonosetron prevent nausea and vomiting in lung cancer chemotherapy.Methods Randomly selected 40 advanced lung cancer chemotherapy patients.divided them into observation group and control group.observed patients with acute vomiting response,vomiting of delay. the nausea classification in two groups、suspend the vomiting prevention of adverse reactions.Results The observation group of patients with acute vomiting and control group had no significant difference（P〉0.05）;delayed vomiting, nausea and control patients,the observation group were significantly higher than those of control group.The adverse reaction in observation group was lower than that in the control group,no significant difference（P〉0.05）.Conclusion In late lung cancer chemotherapy,the curative effect of palonosetron patients with delayed anti-nausea aspects of vomiting,nausea control is better than Aza SiQiong,has the similar effect of the aspect of acute vomiting anti-nausea to Aza SiQiong,little clinical adverse reaction,it is worthy of popularization application.