磁共振扩散峰度成像在肿瘤中的研究进展

扩散峰度成像(diffusional kurtosis imaging,DKI)是一种新兴的基于非高斯分布模型的磁共振技术,创新拓展于扩散加权成像(diffusional weight imaging,DWI)技术与扩散张量成像(diffusional tensor imaging,DTI)基础之上,可定量描述细胞内外水分子非高斯扩散特点,能够较DWI、DTI技术提供更丰富、真实、准确的组织微观结构信息。近年来,DKI逐渐应用于各系统疾病研究,尤其在脑、前列腺等肿瘤中取得了初步成果,展现出良好的临床价值。本文就DKI成像原理、在肿瘤中的应用进展予以综述。

Research progess of diffusional kurtosis imaging in tumour

Diffusional kurtosis imaging (DKI) was an emerging magnetic resonance imaging technology which was base on the model of non-Gaussian distribution, it was also the extension of diffusional weight imaging(DWI) and diffusional tensor imaging (DTI). DKI could describe the non-Gaussian distribution characteristic of hydrone of intracellular and extracellular through quantitative analysis, which can offer more plentiful, real and accurate microstructure information of tissue than DWI and DTI. In recent years, DKI gradually apply to diseases of different systems, had achieved some initial results especially in tumours of brain and prostate, which displayed excellent clinical value. This article proposed to summary the technic principles and aplication advances in tumours for DKI.