Selective Condensation of Aminoacyl Adenylates by Nucleoproteinoid Microparticles |
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| Authors: | Tadayoshi Nakashima and Sidney W. Fox |
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| Affiliation: | .Institute of Molecular Evolution, University of Miami, Coral Gables, Florida 33134;.Department of Biochemistry, University of Miami, Coral Gables, Florida 33134 |
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| Abstract: | Microparticles composed of each of four enzymically synthesized homopolynucleotides and the same lysine-rich proteinoid have been found to influence the condensation of the AMP-anhydrides of each of four amino acids. The conditions of preparation of the particles and other variables of the experiments control the types of reaction. When a specified set of conditions was identified empirically, the incorporation favored the amino acids whose present-day codons are related to the homopolynucleotide in the particle. |
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