小儿原发性肾病综合征并发感染临床分析

目的探讨小儿原发性肾病综合征并发感染的发生率及相关因素。方法回顾分析我院儿科住院的150例原发性肾病综合征患儿中发生感染的临床资料。结果150例中发生院内感染48例，发生院外感染25例，感染率为48．7％，其中呼吸道感染占多数；住院时间超过20d，患儿院内感染的发生率达79．4％，感染与血浆免疫球蛋白（IgG）、白蛋白下降有关。结论肾病综合征患儿易合并院内外感染，感染与住院时间长短、血浆免疫球蛋白以及白蛋白水平有关，缩短住院时间、提高免疫球蛋白、白蛋白水平可减少感染的发生。

Clinical analysis on primary nephrotic syndrome complicated with infection

Objective To explore the incidence of primary nephrotic syndrome complicated with infection in childhood and related factors. Methods To analyse the clinical data of infection in 150 cases hospitalized for primary nephrotic syndrome in Pediatric Department of this hospital. Result Among 150 cases of primary nephrotic syndrome, 48 cases were complicated with nosocomial infection and 25 cases were complicated with community infection. Most of the infections occurred in respiratory tract. The incidence of complication was 79.4% when the period of hospitalization was over 20 days. Nosocomial infection was related to the decrease of serum levels of immunoglobulin G and albumin. Conclusion Primary nephrotic syndrome tends to be commplicated with infection. Infection was related to the duration of hospitalization and serum levels of immunoglobulin and albumin. To shorten the hospitalization time and enhance the levels of immunoglobulin and albumin can reduce the occurrence of infection.