| 水产品中多种氟喹诺酮类药物残留的HPLC测定法 |
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| 引用本文： | 康莉,李勇,陈春晓,丘红梅.水产品中多种氟喹诺酮类药物残留的HPLC测定法[J].职业与健康,2008,24(2):119-121. |
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| 作者姓名： | 康莉 李勇 陈春晓 丘红梅 |
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| 作者单位： | 1. 广东省深圳市疾病预防控制中心,518020
2. 深圳市人民医院 |
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| 摘 要： | 目的建立多种喹诺酮类（FQs）药物同时检测的高效液相色谱方法，建立水产品中（FQs）药物残留提取的前处理方法。方法研究水产品中喹诺酮类药物检测的最佳提取条件，液相色谱条件和荧光检测参数等。结果在该实验条件下，7种FQs类药物检测线性范围0.01～0.50mg/L（沙拉沙星0.10-5.0mg/1），最低检出限0.08-0.36μg/kg，变异系数1.5％～8.6％，样品加标回收率64.0％-93.4％。结论该方法能同时检测水产品中多种（FQs）药物残留，简单、快速、精密度较好、准确灵敏度较高，结果较满意。
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| 关 键 词： | 水产品 氟喹诺酮类 残留 高效液相色谱 |
| 文章编号： | 1004-1257(2008)02-0119-03 |
| 修稿时间： | 2007年4月30日 |
HPLC Method in the Determination of Fluoroquinolone Residues in Aquatic Products |
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| KANG Li,LI Yong,CHEN Chun-xiao,QIU Hong-mei.HPLC Method in the Determination of Fluoroquinolone Residues in Aquatic Products[J].Occupation and Health,2008,24(2):119-121. |
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| Authors: | KANG Li LI Yong CHEN Chun-xiao QIU Hong-mei |
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| Institution: | KANG Li,LI Yong,CHEN Chun-xiao, et al.( Shenzhen Center for Disease Prevention and Control, Guangdong, 518020, China) |
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| Abstract: | Objective] To establish high performance chromatography for the simultaneous determination of multiple fluoroquinolone residues in aquatic products. Methods] The optimal condition of detecting fluoroquinolone residues in the aquatic products, liquid chromatographic condition and fluorescence detection parameter were studies. Results ] Under this experimental condition, the line- ar range of 7 kinds of fluoroquinolone drugs was 0.01 ~ 0.50mg/L; the detection limit was 0.08-0. 36 μg/kg; RSD ranged from 1. 5% to 8.6% ; the labeled recovery rate of the samples was 64.0% ～ 93.4%. Conclusion] This method is simple, rapid, accu- rate and precise in the simultaneous determination of multiple fluoroquinolone residues in aquatic products. |
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| Keywords: | Aquatic products Fluoroquinolone Residue High performance chromatography Determination |
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