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Relationship of administered dose to blood venom levels in mice following experimental envenomation by Russell's viper (Vipera russelli) venom
Authors:U Mg-Mg-Thwin  Y"  >Thein-Than  Y"  >Hla-Pe
Affiliation:1. Nuclear Medicine Division Department of Medical Research, No. 5 Zafar Shah Road, Dagon P.O. Rangoon, Burma;2. Biochemistry Research Division, Department of Medical Research, No. 5 Zafar Shah Road, Dagon P.O. Rangoon, Burma
Abstract:
I125 labelled Russell's viper venom was administered i.m. into mice at various doses. Radioactivity in the blood at different intervals was determined and related to the amount injected. A mathematical equation was formulated to represent the relationship of administered dose to blood venom levels. This study suggests that the derivation of such an equation is also possible in humans in order to predict the amount envenomated.
Keywords:To whom correspondence should be addressed.
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