循证药学在碳青霉烯类药物临床应用的研究

目的：为解决临床用药问题，查找循证医学及循证药学证据，比较亚胺培南和美罗培南的安全性以及美罗培南的输注方法改进。方法：检索数据库，查找相关的系统评价，随机对照实验等，并对所获得的证据进行质量评价。结果：美罗培南的肝损害发生率比亚胺培南略高，并且不良反应与药物应用剂量无关。结论：采用美罗培南对难治性耐药茵应3h连续静脉滴注有较好效果。

Follows the card pharmacy in the carbon blue mildew alkenes medicine clinical practice research

Objective： To solve the problems of clinical medicine, evidence-- based medicine and evidence -- based medicine to find evidence to compare the safety of imipenem and meropenem and meropenem infusion of ways to improve. Methods：Database searches to find relevant systematic reviews, randomized controlled experiments, and the evidence obtained to evaluate the quality. Results： Mcropenem incidence of liver damage is slightly higher than imipenem,and adverse reactions and drug use independent of dose. Con- elusion：Meropenem resistant refractory ah continuous intravenous infusion should have better results.