Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib |
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| Authors: | Daniela Alexandru Denise K. Van Horn Daniela Annenelie Bota |
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| Affiliation: | (1) Department of Neurological Surgery, University of California, Irvine, Irvine, CA, USA;(2) Department of Pathology, Hoag Hospital, Newport Beach, CA, USA;(3) Department of Neurology, University of California, Irvine, Irvine, CA, USA; |
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| Abstract: | Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system. |
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