继发性甲旁亢甲状旁腺全切术后嗓音变化研究

目的 观察继发性甲状旁腺功能亢进甲状旁腺全切术后患者嗓音的变化。 方法 选择继发性甲状旁腺功能亢进患者29例,其中男18例,平均(43±12)岁;女11例,平均(50±12)岁。患者术前及术后第5天测试F₀、Jitter、Shimmer和噪比等嗓音分析指标,以及最大发音声时(MPT)和血钙浓度。测试术前术后第1天的血清甲状旁腺素水平(PTH)值。 结果 患者F₀、Jitter、Shimmer和谐噪比术前术后差异无统计学意义,而MPT术后明显缩短(P<0.05)。 结论 继发性甲状旁腺功能亢进甲状旁腺全切术后在维持血钙的情况下最大发音时间均有明显缩短,而基频及频率微扰及振幅微扰以及噪比没有变化。

Voice changes after parathyroidectomy in patients with secondary hyperparathyroidism

Objective To investigate the changes in voice after parathyroidectomy in patients with secondary hyperparathyroidism. Method This study involved 29 patients, including 11 women(mean age, 50±12 years)and 18 men(mean age, 43±12 years). All patients underwent computerized voice analysis for F₀, jitter, shimmer, and harmony-to-noise ratio(HNR)and maximum phonation time(MPT)and serum calcium concentration assessment preoperatively and 5 days postoperatively. The serum parathyroid hormone concentration was measured pre- and post-operatively. Results There was no difference between the pre- and post-operative F₀, jitter, shimmer, and HNR. The MPT decreased after parathyroidectomy(P<0.05). Conclusion The MPT decreased significantly after parathyroidectomy remaining serum calcium concentration on secondary hyperparathyroidism. However, no changes were observed in F₀, jitter, shimmer, and HNR.