利多卡因和沙丁胺醇超声雾化吸入治疗中、重度哮喘的疗效

目的: 评价利多卡因和沙丁胺醇联合雾化吸入治疗中、重度哮喘的疗效和安全性.方法: 选择符合中、重度哮喘诊断的成年入院病例60例,随机分为治疗组和对照组各32例.治疗组联合应用利多卡因和沙丁胺醇超声雾化吸入治疗哮喘,对照组单纯应用沙丁胺醇超声雾化吸入.测定入院当天、治疗2周后的FEV1、PEFR值.结果: 治疗组和对照组临床控制率分别为75.0%和50.0%(P<0.05);治疗2周后治疗组肺功能有明显改善.结论: 联合应用利多卡因和沙丁胺醇超声雾化吸入治疗中、重度哮喘较单纯应用沙丁胺醇效果良好,改善肺功能显著.

Evluation Eavluation of Lidocaine and Salbutamol in Severe Bronchial Asthma via Ultrasonic Nebulizer Inhalation

Objective: To evaluate efficacy of lidocaine and salbutamol in severe bronchial asthma via ultrasonic nebulizer inhalation.Method: Using control trial,64 cases were treated by lidocaine and salbutamol via ultrasonic nebulizer inhalation.Clinical data,including FEV1,PEFR collected in the first day and the 14 day, were analyzed.Result: The clinical control rates of two groups were 75.0% while in the matched control group it is 50.0% ( P < 0.05 ).There was a good improvement of pulmonary funtion in the trial group after treatment for 2 weeks'.Conclusion: Lidocaine and salbutamol are benefit to severe bronchial asthma via ultrasonic mist spray treatment.