| 大肠癌药物疗效及预后预测的分子指标研究进展 |
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| 引用本文： | 梁军,刘自民,姜韬. 大肠癌药物疗效及预后预测的分子指标研究进展[J]. 临床肿瘤学杂志, 2009, 14(11): 961-968 |
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| 作者姓名： | 梁军 刘自民 姜韬 |
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| 作者单位： | 青岛大学医学院附属医院肿瘤治疗中心 |
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| 摘 要： | 大肠癌是人类最常见的恶性肿瘤之一，药物治疗在大肠癌的综合治疗中扮演重要的角色。化疗药物和靶向药物的联合使用，使大肠癌的药物治疗有效率明显提高，但仍有很大一部分患者对于化疗药物无反应。寻找化疗疗效预测以及预后的分子指标，选择能从化疗受益的优势人群就非常重要。本文就大肠癌药物治疗疗效预测及预后分子指标的研究进展做一综述。
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| 关 键 词： | 大肠肿瘤 药物治疗 分子指标 |
| 收稿时间： | 2009-09-29 |
| 修稿时间： | 2009-10-21 |
Progression of molecular factors as predictors of clinical outcome with drug therapy in colorectal cancer |
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| LIANG Jun,LIU Zi-min,JIANG Tao. Progression of molecular factors as predictors of clinical outcome with drug therapy in colorectal cancer[J]. Chinese Clinical Oncology, 2009, 14(11): 961-968 |
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| Authors: | LIANG Jun LIU Zi-min JIANG Tao |
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| Affiliation: | .( Cancer Center, the Affiliated Hospital of Medical College of Qingdao University, Qingdao 266003, China) |
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| Abstract: | Colorectal cancer is one of the most common malignant tumors,drug treatment plays an important role in the comprehensive treatment.The combination of chemotherapy drugs and target drugs has markedly improved response rate.But there is still a significant portion of patients showed non-response to drug treatment.Searching for the molecular indicators of prognosis and predict of chemotherapy,and then choosing the people who can benefit from drug therapy are very important.Updates of prognostic and predictive molecular factors in colorectal cancer are reviewed in this article. |
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| Keywords: | Colorectal carcinomas Drug therapy Molecular factors |
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