| 海洛因瘾康复期使用纳曲酮防止复吸100例 |
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| 引用本文： | 苏木金,刘华承,邓忭明,王立功,董小岩. 海洛因瘾康复期使用纳曲酮防止复吸100例[J]. 中国新药与临床杂志, 1997, 0(3) |
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| 作者姓名： | 苏木金 刘华承 邓忭明 王立功 董小岩 |
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| 作者单位： | 中国人民解放军广州疗养院 |
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| 摘 要： | 目的：观察盐酸纳曲酮防止海洛因依赖者戒毒后复吸疗效。方法：ｍｏ１～２每日口服纳曲酮片１５～２０ｍｇ，ｍｏ３～４服１０～１５ｍｇ，ｍｏ５～６服５～１０ｍｇ，６ｍｏ为一个疗程。结果：３ｍｏ复吸率为４２％，６ｍｏ复吸率为７２％，显效率为４５％，有效率为７４％。结论：服药后可明显减轻海洛因依赖者对毒品渴求感和焦虑症状，降低复吸率。纳曲酮本身无依赖性，副作用轻微。
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| 关 键 词： | 纳曲酮；海洛因瘾；药物评价 |
Use of naltrexone to avoid relapse in 100 addicts of heroin during rehabilitation |
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| SU Mu-Jin,LIU Hua-Cheng,DENG Bian-Ming,WANG Li-Gong,DONG Xiao-Yan. Use of naltrexone to avoid relapse in 100 addicts of heroin during rehabilitation[J]. Chinese Journal of New Drugs and Clinical Remedies, 1997, 0(3) |
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| Authors: | SU Mu-Jin LIU Hua-Cheng DENG Bian-Ming WANG Li-Gong DONG Xiao-Yan |
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| Abstract: | AIM: To observe the effect of naltrexone hydrochloride avoiding relapse of heroin. METHODS: The daily dosage in the mo 1-2 was 15-20 mg, 10-15 mg in the mo 3-4, and 5-10 mg in the mo 5-6. The period of treatment was 6 mo. RESULTS: The obvious effective rate was 45%, the effective rate was 74%. The relapse rate in 3 mo was 42% and 72% in 6 mo. CONCLUSION: The thirsty and dysphoric symptoms of heroin dependence is decrease obviously after naltrexone hydrochloride treatment. And the relapse rate of heroin also decrease obviously, side effects are mild. |
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| Keywords: | naltrexone heroin dependence drug evaluation |
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