不同浓度对比剂对64层螺旋CT冠状动脉成像质量影响

目的：探讨不同浓度对比剂对64层螺旋CT冠状动脉成像质量影响。方法：回顾性分析入住我院的90例行64层螺旋CT冠状动脉成像患者的临床资料，将其随机地均分为A、B两组，各为45例。A组采用方案：固定对比剂用量（70mL Iopamidol 370），B组采用方案：根据患者的实际体重来选择对比剂的用量（0．8mL／kg）。对多平面重组图像以及横断面图像的质量进行评价，比较两种方案下的图像质量、对比剂的增强水平以及对比剂的实际用量。结果：B组质量分级、质量评分（4．45±0．67）分、左回旋支（LAD）近段、左回旋支（LCX）近段、右冠动脉（RCA）近段、后降支（PDA）、右冠动脉（RCA）远段、主动脉根部、主肺动脉、左室、右室对比剂增强效果明显优于A组；对比剂用量（50．24±4．65）mL明显低于A组，差异具有统计学意义（P〈0．05）。B组各体重组增强效果相对固定于一定阈值范围。结论：与固定对比剂的应用方案之间进行对比，在冠状动脉成像之中按照患者的体重来选择对比剂的用量能够明显改善冠状动脉成像的质量，对比剂用量明显减少，同时还能够助于获取更佳且更为一致性的对比剂增强水平，应对该技术加以推广并应用。

Coronary image quality of 64-slice CT using different concentrations of contrast agent

Objective：To explore different coronary image quality of 64-slice CT using different concentrations of contrast agents. Methods： A retrospective analysis of 90 cases underwent 64-slice spiral CT examination was conducted, and these cases were randomly divided into group A and group B. Fixed amount of contrast agent was given （70 mL Iopamidol 370） for group A, and while for group B, the dosage of contrast agent was 0.8 mL/kg body weight. Coronary image quality, enhanced degree and consumed amount of contrast agent were compared between the two groups. Results： In group B, image quality grading, quality score （4.45±0.67）, left circumflex artery （LAD） proximal artery, left circumflex artery （LCX）, proximal segment of right coronary artery （RCA）, posterior descending artery （PDA）, right coronary artery （RCA） distal aortic root, the main pulmonary artery, left ventricle and right ventricle were all better enhanced under the CT compared with those of group A. Medium consumed dosage of contrast agent was （50. 24±4.65） mL, significant lower than that of group A （P（ 0.05）. For patients with different body weights, the enhanced effects were within a certain threshold value. Conclusion： Compared with fixed dosage of contrast agent, coronary images produced with amount of contrast agent in accordance with the patient＇s body weight shows better quality with consistent high level, this method is worthy of application in large scale.