白内障患者血清、房水及泪液IL-2、sIL-2R、NO、TAC及SOD的变化

目的：研究白内障患者血清、房水及泪液白介素-2（IL-2）、可溶性白介素-2受体（sIL-2R）、一氧化氮（NO）、总抗氧化能力（TAC）及超氧化物歧化酶（SOD）的变化。方法：选取2011年11月-2013年9月本院收治的60例白内障患者为观察组，并以同期60例眼外伤患者为对照组，比较两组血清、房水及泪液IL-2、sIL-2R、NO、TAC及SOD水平，并比较不同白内障分期者各指标的检测水平。结果：观察组血清、房水及泪液IL-2、TAC及SOD水平均低于对照组，sIL-2R及NO水平高于对照组，且不同分期者血清、房水及泪液检测水平也存在明显差异，其中房水IL-2低于血清及泪液，sIL-2R则高于血清及泪液，差异均有统计学意义（P均〈0．05）。结论：白内障患者血清、房水及泪液IL-2、sIL-2R、NO、TAC及SOD变化均较大，并且受分期影响较大，房水中的炎性反应状态更为明显。

Change of serum,aqueous humor and tear IL-2, sIL-2R,NO, TAC,and SOD in patients with cataract

Objective： To study the change of serum,aqueous humor and tear IL-2, sIL-2R, NO, TAC, and SOD of patients with cataract. Methods：A total of 60 patients with cataract in our hospital from November 2011 to September 2013 were selected as observation group, and 60 patients with eye traumas as the control group, then the serum, aqueous humor and tear IL-2, sIL-2R, NO,TAC, and SOD of two groups were detected and compared,and the detection levels of patients with different stages were also compared. Results：The serum, aqueous humor and tear IL-2, TAC,and SOD of observation group were all significantly lower than those of control group,the sIL-2R and NO were all significantly higher than those of control group. There were significant differences in the serum, aqueous humor and tear detection levels of patients at different stages （P〈0.05）. The aqueous humor IL-2 were significantly lower than those of serum and tear, the sIL-2R were significantly higher than those of serum and tear （P〈0.05）. Conclusion： The change of serum, aqueous humor and tear IL-2, sIL-2R, NO,TAC,and SOD of patients are all great,and are significantly influenced by stages,especially the inflammatory response state of aqueous humor.