| 肺癌患者化疗前后血浆D-二聚体测定的临床意义 |
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| 引用本文： | 王朝霞,王科明,施为建,沈群,周荣富,潘勤,王继荣. 肺癌患者化疗前后血浆D-二聚体测定的临床意义[J]. 中华肿瘤防治杂志, 2000, 7(4): 363-364 |
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| 作者姓名： | 王朝霞 王科明 施为建 沈群 周荣富 潘勤 王继荣 |
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| 作者单位： | 1. 江苏省南京医科大学第二附属医院肿瘤科,南京市,210011
2. 江苏省南京医科大学第二附属医院血液科,南京市,210011 |
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| 摘 要： | 目的 :探讨肺癌患者血浆D -二聚体水平与化疗疗效的关系。方法 :采用胶体金方法测定 35例肺癌患者化疗前后血浆D -二聚体的含量。结果 :肺癌患者化疗前血浆D -二聚体水平显著高于正常人 (P <0 0 0 1) ,化疗后有效组 (CR PR)D -二聚体含量显著低于化疗前 (P <0 0 0 1) ,化疗后稳定组D -二聚体含量与化疗前相比 ,差异无显著性 (P <0 0 5) ,化疗后进展组D -二聚体含量明显高于化疗前 (P <0 0 0 1)。结论 :血浆D -二聚体的水平高低可作为肺癌判断预后、观察疗效的一个指标
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| 关 键 词： | 肺肿瘤 D-二聚体 预后 |
| 修稿时间： | 2000-03-10 |
The Prognostic Significance of Plasma D-dimer Concentration in Patients with Lung Cancer |
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| WHNG Zhaoxia,WANG Kenming,SHI Weijian,et al.. The Prognostic Significance of Plasma D-dimer Concentration in Patients with Lung Cancer[J]. Chinese Journal of Cancer Prevention and Treatment, 2000, 7(4): 363-364 |
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| Authors: | WHNG Zhaoxia WANG Kenming SHI Weijian et al. |
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| Affiliation: | WHNG Zhaoxia,WANG Kenming,SHI Weijian,et al.Department of Oncology,The second Affiliated Hospital of Nanjing Medical University,Nanjing 210011 |
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| Abstract: | Objective:To investigate the relationship between plasma Ddimer and the effect of chemotherapy of patients with lung cancer.Methods:Colloidal gold was used to determine the Ddimer concentration in plasma samples.Results:The level of Ddimer in 35 new lung cancer patients was significantly higher than that of normal control(P<0001).After chemotherapy,the level of Ddimer in patients with CR and PR was markedly reduced(P<0001),but increased(P<0001)in PD cases ,and not changed in SD patients.Conclusions:The level of plasma Ddimer can be used in predicting the effects of chemotherapy of lung cancer. |
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| Keywords: | lung cancer D-dimer prognosis |
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