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Plasmablastic Lymphoma of the Small Intestine in an HIV- and EBV-negative Patient |
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| Authors: | Yuka Fukuo Tomoyoshi Shibuya Karin Ashizawa Kentaro Ito Michio Saeki Hirofumi Fukushima Masahito Takahashi Kei Nomura Koki Okahara Keiichi Haga Yoichi Akazawa Osamu Nomura Kanako Ogura Hironao Okubo Akihito Nagahara |
| Affiliation: | 1.Department of Gastroenterology, Juntendo University Nerima Hospital, Japan; 2.Department of Gastroenterology, Juntendo University, Japan; 3.Department of Diagnostic Pathology, Juntendo University Nerima Hospital, Japan |
| Abstract: | Plasmablastic lymphoma (PBL) is a rare aggressive B-cell lymphoproliferative disorder that is strongly associated with immunodeficiency, most often with human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) infection, and that mainly occurs in the oral cavity. Although some clinical features can lead to a diagnosis, PBL in an extraoral site is difficult to suspect clinically in a patient who is HIV negative. The small intestine as a site of PBL has also been described very rarely. We herein present a rare case of PBL of the small intestine in an 85-year-old HIV- and EBV-negative male. |
| Keywords: | plasmablastic lymphoma small intestine HIV Epstein-Barr virus |