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SLC2A3 single-nucleotide polymorphism and duplication influence cognitive processing and population-specific risk for attention-deficit/hyperactivity disorder
Authors:Sören Merker  Andreas Reif  Georg C. Ziegler  Heike Weber  Ute Mayer  Ann-Christine Ehlis  Annette Conzelmann  Stefan Johansson  Clemens Müller-Reible  Indrajit Nanda  Thomas Haaf  Reinhard Ullmann  Marcel Romanos  Andreas J. Fallgatter  Paul Pauli  Tatyana Strekalova  Charline Jansch  Alejandro Arias Vasquez  Jan Haavik  Marta Ribasés  Josep Antoni Ramos-Quiroga  Jan K. Buitelaar  Barbara Franke  Klaus-Peter Lesch
Affiliation:1. Division of Molecular Psychiatry, ADHD Clinical Research Unit, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany

Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany;2. Division of Molecular Psychiatry, ADHD Clinical Research Unit, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany;3. Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany;4. Department of Psychology I, University of Würzburg, Würzburg, Germany

Department of Child and Adolescent Psychiatry, University of Tübingen, Tübingen, Germany;5. K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Bergen, Norway;6. Department of Human Genetics, Biozentrum, University of Würzburg, Würzburg, Germany;7. Max-Planck Institute for Molecular Genetics, Berlin, Germany

Bundeswehr Institute of Radiobiology, University of Ulm, Ulm, Germany;8. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany;9. Department of Psychology I, University of Würzburg, Würzburg, Germany;10. Division of Molecular Psychiatry, ADHD Clinical Research Unit, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany

Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Department of Translational Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands;11. Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands;12. Division of Psychiatry, Haukeland University Hospital, Bergen, Norway

Department of Biomedicine, K.G. Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Bergen, Norway;13. Psychiatric Genetics Unit, Institute Vall d'Hebron Research (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain

Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Spain;14. Psychiatric Genetics Unit, Institute Vall d'Hebron Research (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain

Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Spain

Department of Psychiatry and Legal Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain;15. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands;16. Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands

Abstract:
Keywords:Attention-deficit/hyperactivity disorder  glucose transporter  SLC2A3  single-nucleotide polymorphisms  duplication  copy number variants  energy homeostasis  frontostriatal network
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