| 自拟清肺化痰汤联合莫西沙星治疗外寒内热型社区获得性肺炎疗效观察 |
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| 引用本文： | 曲志成,曹迎,张红升,徐向东,裴晓璐,姚卫海.自拟清肺化痰汤联合莫西沙星治疗外寒内热型社区获得性肺炎疗效观察[J].北京中医药,2019,38(4):328-331. |
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| 作者姓名： | 曲志成 曹迎 张红升 徐向东 裴晓璐 姚卫海 |
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| 作者单位： | 首都医科大学附属北京中医医院急诊科,北京,100010;首都医科大学附属北京中医医院急诊科,北京,100010;首都医科大学附属北京中医医院急诊科,北京,100010;首都医科大学附属北京中医医院急诊科,北京,100010;首都医科大学附属北京中医医院急诊科,北京,100010;首都医科大学附属北京中医医院急诊科,北京,100010 |
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| 摘 要： | 目的观察自拟清肺化痰汤联合莫西沙星治疗外寒内热型社区获得性肺炎(CAP)的临床疗效。方法本研究为探索性、前瞻性随机对照研究,将70例外寒内热型社区获得性肺炎患者随机分为观察组与对照组,每组各35例。对照组采用莫西沙星注射液静脉滴注治疗,观察组在对照组基础上加服自拟清肺化痰汤每次200mL,每日3次。2组疗程均为7天。观察比较2组患者热退时间、治疗前后咳嗽VAS评分、治疗前后2组患者血常规、C反应蛋白(CRP)、降钙素原(PCT)水平、总体疗效以及安全性评价。结果观察组退热时间(1.34±0.93)d,对照组(2.91±1.17)d,差异有统计学意义(P<0.05)。治疗后,2组咳嗽VAS评分较治疗前均明显降低(P<0.05),观察组更为明显(P<0.05)。2组患者治疗后血WBC、CRP、PCT水平较治疗前均明显降低;观察组CRP较对照组降低更明显(P<0.05)。观察组总有效率为93.94%,对照组为84.85%(P<0.05)。观察组2例患者出现输液局部皮肤瘙痒,对照组1例患者出现输液局部皮肤瘙痒,1例患者出现失眠。结论清肺化痰汤联合莫西沙星能够缩短CAP患者退热时间,缓解咳嗽症状,并能有效抑制炎性反应,具有良好的临床疗效。
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| 关 键 词： | 清肺化痰汤 社区获得性肺炎 外寒内热证 中西医结合 临床观察 |
Clinicalefficacy of self-made Qingfei Huatan Decoction combined with moxifloxacin in the treatment of exterior cold and interior heat type of community-acquired pneumonia |
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| QU Zhi-cheng,CAO Ying,ZHANG Hong-sheng,XU Xiang-dong,PEI Xiao-lu,YAO Wei-hai.Clinicalefficacy of self-made Qingfei Huatan Decoction combined with moxifloxacin in the treatment of exterior cold and interior heat type of community-acquired pneumonia[J].Beijing Journal of Traditional Chinese Medicine,2019,38(4):328-331. |
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| Authors: | QU Zhi-cheng CAO Ying ZHANG Hong-sheng XU Xiang-dong PEI Xiao-lu YAO Wei-hai |
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| Institution: | (Department of Emergency Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University,Beijing 100010,China) |
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| Abstract: | QU Zhi-cheng;CAO Ying;ZHANG Hong-sheng;XU Xiang-dong;PEI Xiao-lu;YAO Wei-hai(Department of Emergency Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University,Beijing 100010,China) |
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| Keywords: | Qingfei Huatan Decoction community-acquired pneumonia exterior cold and interior heat syndrome integrated Chinese and western medicine clinical observation |
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