| 多肽类示踪技术在乳腺癌诊治中的应用进展 |
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| 引用本文： | 江波,刘璐. 多肽类示踪技术在乳腺癌诊治中的应用进展[J]. 国际放射医学核医学杂志, 2008, 33(1): 5-8. DOI: 10.3760/cma.j.issn.1673-4114.2009.01.005 |
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| 作者姓名： | 江波 刘璐 |
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| 作者单位： | 东南大学医学院核医学技术研究所,南京,210009; |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 核素分子诊治乳腺癌在近几年发展迅速,是研究的热点.放射性核素标记的多肽受体显像是核医学中最年轻、最有活力的分支领域.当前有代表性的前沿多肽类示踪药物包括生长抑素类似物、16α-18F-17β-雌二醇、血管活性肠肽、白细胞介素11类似物环九肽、顺式11β-甲氧基-17α-123I-碘乙烯雌二醇等数种.该文综述各种多肽类药物在乳腺癌诊治中的最新进展.
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| 关 键 词： | 乳腺肿瘤 肽类 放射疗法 受体显像 |
Application researched progress of micromolecule polypeptide technology in diagnosis and therapy of breast cancer |
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| JIANG Bo,LIU Lu. Application researched progress of micromolecule polypeptide technology in diagnosis and therapy of breast cancer[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2008, 33(1): 5-8. DOI: 10.3760/cma.j.issn.1673-4114.2009.01.005 |
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| Authors: | JIANG Bo LIU Lu |
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| Abstract: | Nuclide molecule diagnosis and therapy breast cancer is developing quite quickly in recent years, and is the hot spot of study and research. The developing of polypeptide receptor labelling by radioactivity nuclide is the most active and youngest territory branch of nuclear medicine. The nearest representative of polypeptide drug including somatostatin analogue, 18F-fluoroestradiol, vasoactive intestinal peptide, interleukin-11 analogs nine-circellus polypeptide, 11 -metoxy-17 -123I-iodovinylestradiol, this review the nearest progress of every polypeptide drug in diagnosis and therapy of breast cancer respectively. |
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| Keywords: | Breast neoplasmsPeptidesRadiotherapyReceptor image |
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