| 2型糖尿病血尿酸水平及其并发症相关因素分析 |
| |
| 引用本文： | 薛长春. 2型糖尿病血尿酸水平及其并发症相关因素分析[J]. 中国全科医学, 2007, 10(22): 1868-1869 |
| |
| 作者姓名： | 薛长春 |
| |
| 作者单位： | 首都医科大学大兴医院内分泌科,北京市,102600 |
| |
| 摘 要： | 目的探讨血尿酸水平对糖尿病代谢及其并发症的影响。方法选择279例2型糖尿病患者,按血尿酸水平分成尿酸水平偏低或正常组(A组)和高尿酸组(B组),检测并比较两组患者的生化指标及其并发症发生率。结果两组患者性别、体重指数、胰岛素抵抗指数和空腹血浆胰岛素、三酰甘油、总胆固醇、高密度脂蛋白胆固醇水平及24h尿微量白蛋白间差别均有统计学意义(P<0.05);且高血压、冠心病和肥胖的发生率间差别亦均有统计学意义(P<0.01)。结论高尿酸血症加重了2型糖尿病患者的代谢紊乱和胰岛素抵抗,是引起2型糖尿病相关并发症的危险因素。
|
| 关 键 词： | 糖尿病,2型 高尿酸血症 胰岛素抵抗 代谢综合征 |
| 文章编号： | 1007-9572（2007）22-1868-02 |
| 修稿时间： | 2007-09-15 |
Analysis of the Complications and Factors Related to Serum Uric Acid in Patients with Type 2 Diabetes |
| |
| XUE Chang-chun. Analysis of the Complications and Factors Related to Serum Uric Acid in Patients with Type 2 Diabetes[J]. Chinese General Practice, 2007, 10(22): 1868-1869 |
| |
| Authors: | XUE Chang-chun |
| |
| Affiliation: | Department of Endocrinology;Daxing Hospital of Capital Medical University;Beijing 102600;China |
| |
| Abstract: | Objective To study the factors related to serum uric acid in type 2 diabetic patients and to investigate the effect of serum uric acid levels on the metabolism and complications.Methods 279 cases were divided into 2 groups according to their uric acid level,then the relationship between serum uric acid and metabolic parameters and complications in two groups were observed.Results Patients with hyperuricacidemia in types 2 diabetes had markedly higher the rate of male,BMI,Fins,HOMA-IR,TG,TC,UAE and the incidence of hypertension,coronary heart disease and obesity,markedly lower HDL-C.Conclusion The hyperuricemia might be a high risk factor of type 2 diabetes for complications. |
| |
| Keywords: | Diabetes mellitus type 2 Hyperuricemia Insulin resistance Metabolic syndrome |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
