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Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer
Authors:Guo Jian  Zhou Songwen  Zhang Ling  Deng Qinfang  Zhang Jie  Tang Liang  Zhou Caicun
Affiliation:(1) Department of Oncology, Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, People’s Republic of China
Abstract:

Purpose  

Recently, mutations in the epidermal growth factor receptor (EGFR) gene were reported to correlate with EGFR tyrosine kinase inhibitor response in advanced non-small cell lung cancer (NSCLC). In this study, we attempted to detect EGFR mutations in plasma and pleural effusion samples and to make clear its correlations with gefitinib response and survival in NSCLC patients.
Keywords:
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