| 决明子降血脂有效部位的研究 |
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| 引用本文： | 张加雄,万丽,胡轶娟,屈巧玲,师健友. 决明子降血脂有效部位的研究[J]. 时珍国医国药, 2006, 17(6): 904-905 |
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| 作者姓名： | 张加雄 万丽 胡轶娟 屈巧玲 师健友 |
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| 作者单位： | 成都中医药大学药学院,四川,成都,611730 |
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| 基金项目： | 四川省中医药管理局中医药科学技术研究资助专项项目（No.2003A05） |
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| 摘 要： | 目的研究决明子降血脂的有效部位。方法采用系统溶剂提取法对决明子进行分部位提取,制得决明子提取物。建立小鼠高脂血症模型,对各提取物进行降血脂药效学研究,确定决明子降血脂有效部位。结果决明子正丁醇提取物具有明显的降血脂作用,能显著降低高脂血症小鼠血清总胆固醇(TC)和甘油三酯(TG)。结论正丁醇提取物为决明子降血脂有效部位。
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| 关 键 词： | 决明子 血脂 有效部位 |
| 文章编号： | 1008-0805（2006）06-0904-01 |
| 收稿时间： | 2005-07-20 |
| 修稿时间： | 2006-02-27 |
Study on the Effective Part of Reducing Blood Lipid in Semen Cassiae |
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| ZHANG Jia-xiong,WAN Li,HU Yi-juan,QU Qiao-ling,SHI Jan-you. Study on the Effective Part of Reducing Blood Lipid in Semen Cassiae[J]. Lishizhen Medicine and Materia Medica Research, 2006, 17(6): 904-905 |
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| Authors: | ZHANG Jia-xiong WAN Li HU Yi-juan QU Qiao-ling SHI Jan-you |
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| Affiliation: | College of Pharmacy, Chengdu University of TCM, Chengdu 611730, China |
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| Abstract: | ObjectiveTo study the effective part of reducing blood lipid in Semen Cassiae.MethodsThe extracts of Semen Cassia were processed by dissolvent subsectionextracting,and then adopt hyperlipidemia model by mice to study the pharmacological effect of the different extracts from Semen Cassiae.ResultsThe n-BuOH extracts have obvious action of reducing blood lipid.It can notably lower total cholesterin(TC)and glycerinum(TG) in serum from mice of hyperlipidemia.Conclusionn-BuOH extracts is the active part of reducing blood lipid in Semen Cassiae. |
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| Keywords: | Semen Cassiae Blood Lipid Effective Part |
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