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F/T比值在前列腺癌筛选中的应用价值
引用本文:马云波,李仁寿,孙茸,孙瑞利,赵守国.F/T比值在前列腺癌筛选中的应用价值[J].临床泌尿外科杂志,2002,17(4):159-160.
作者姓名:马云波  李仁寿  孙茸  孙瑞利  赵守国
作者单位:聊城市人民医院泌尿外科,山东,聊城,252000
摘    要:目的:评价F/T比值在前列腺癌筛选中的作用。方法:运用直肠指检、B超、PSA、PSA密度(PSAD)、F/T比值对389例行健康体检的50岁以上男性进行前列腺癌筛选,并对各项方法的准确性、特异性、敏感性进行比较。结果:共检出前列腺癌15例,其中F/T比值在敏感性不降低的情况下,其特异性明显优于PSA和PSAD,特别是在PSA的诊断灰区能很好地将良、恶性病变区分开来,使将近50%的可疑患者免受活检。结论:F/T比值是前列腺癌筛选的有效手段。

关 键 词:F/T比值  前列腺癌  筛选  前列腺特异抗原  F/T比值
文章编号:1001-1420(2002)04-0159-02
修稿时间:2000年7月5日

The ratio of free to total prostate specific antigen: Role in screening for prostatic carcinoma
MA Yunbo,LI Renshou,SUN Rong,SUN Ruili,ZHAO Shouguo.The ratio of free to total prostate specific antigen: Role in screening for prostatic carcinoma[J].Journal of Clinical Urology,2002,17(4):159-160.
Authors:MA Yunbo  LI Renshou  SUN Rong  SUN Ruili  ZHAO Shouguo
Institution:MA Yunbo 1 LI Renshou SUN Rong 1 SUN Ruili 1 ZHAO Shouguo 1
Abstract:Purpose:To evaluate the role of free/total PSA ratio in the screening of prostatic carcinoma.Methods:Rectal examination, B ultrasound, PSA, PSAD and free/total PSA ratio were used to screen prostatic carcinoma in 389 cases.Results:Among them, 15 cases of prostatic carcinoma was founded, and the sensitivity for cancer detection of free/total PSAratio was the same as PSA and PSAD, but it's specificity was statistically higher than that of PSA and PSAD, especially in the diagnostic gray zone of total PSA, free/total PSA ratio can differentiate prostatic carcinoma from benign patients readily.Conclusions:Free/total PSA ratio was a good parameter to screen prostatic carcinoma .
Keywords:Prostatic neoplasms  Prostate specific antigen  Screen  F/T ratio
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