PET应用于胃癌病情评估的可行性研究

目的 探讨PET显像在胃癌病情评估中的作用。方法 将23例胃癌患者术前PET全身显像结果与手术探查、活检或胃镜检查明确的肿瘤分型、分期、转移等情况进行对照。结果 PET对胃癌原发灶的诊断准确率达87.0%。以半定量指标SUVmean和SUVmax大于2．5为诊断标准，本组PET诊断准确率分别为86．2％(19／23)和91．3％(21／23)。对淋巴结转移检测准确率为78．9%(15／19)，对远处转移病灶诊断准确率为7／8。结论 PET对胃恶性肿瘤原发灶和远处转移病灶检测较为敏感，为胃癌诊断、手术方法和治疗原则的选择提供了有价值的参考依据。

Diagnostic value of positron emission tomography in gastric malignancy:a preliminary study

Objective To evaluate the diagnostic value of positron emission tomography(PET) with the use of 18 F-fluorodeoxyglucose(FDG) in patients with gastic malignancy. Methods 18 F-FDG PET examination was performed for twenty three patients suspected to be suffering from gastric malignancy,and the results were evaluated against histopathological staging. Results The diagnostic accuracy of primary lesion by PET was 87.0%. When using a mean standard uptake value (SUVmear and SUVmax) with a cut-off of 2.5,the sensitivity was 86.2%(19/23)and 91.3%(21/23),respectively. The accuracy in identifying lymph node metastases and distant metastases by PET was 78.9%(15/19) and 7/8,respectively. Conclusion PET scanning is sensitive in the diagnosis of primary malignant lesion and metastatic lesion in patients suspected to have gastric cancer. It provides a valuable reference in the diagnostic evaluation,option of surgical strategy,and treatment in patients with gastric carcinoma.