Idiopathic portal hypertension associated with systemic lupus erythematosus |
| |
Authors: | Hitoshi Inagaki Toshiaki Nonami Takatsugu Kawagoe Takaya Miwa Jiro Hosono Tsuyoshi Kurokawa Akio Harada Akimasa Nakao Hiroshi Takagi Harumi Suzuki Junichi Sakamoto |
| |
Institution: | (1) Department of Surgery, Aichi Prefectural Hospital, 18 Kuriyado, Kakemachi, Okazaki 444-0011, Japan, JP;(2) Second Department of Surgery, Nagoya University, Nagoya, Japan, JP |
| |
Abstract: | A case of idiopathic portal hypertension (IPH) associated with systemic lupus erythematosus (SLE) is reported in a 38-year-old
man who had been diagnosed with SLE and treated for 18 years. Esophageal varices, found in 1994 on endoscopic examination,
had been followed up for 2 years. On July 16, 1996, he was admitted to Nagoya University Hospital because there was a high
risk of bleeding from the esophageal varices due to severe thrombocytopenia. As partial splenic embolization had temporarily
controlled the thrombocytopenia, splenectomy and devascularization of the stomach vessels were performed after endoscopic
ligation of the esophageal varices. Histological specimens of wedge biopsied liver showed chronic inactive hepatitis without
cirrhosis. The presence of anticardiolipin antibody, indicated by positivity for lupus anticoagulant, was suggestive of the
presence of a common immunological mechanism in the etiology of SLE and IPH.
Received: January 20, 1999 / Accepted: July 23, 1999 |
| |
Keywords: | : portal hypertension systemic lupus erythematosus anticardiolipin antibody |
本文献已被 PubMed SpringerLink 等数据库收录! |
|