麻黄生物碱提取工艺改进

目的：设计考察一种新的麻黄生物碱提取生产工艺。方法：在碱性条件下将生物碱盐转化为生物碱，用二甲苯提取，2％草酸将生物碱转化为草酸盐后进行萃取，在工厂原有设备基础上回收循环利用二甲苯。采用析因试验确定最佳提取条件。结果：由1kg麻黄草得到约6g伪麻黄碱粗品，产率约0．6％。结论：初步确定了用二甲苯提取麻黄中生物碱的可能性。

Improvement of the technological extraction of alkaloids in herba ephedrae

Objective: To investigate a new way of the technological extraction of alkaloids in herba ephedrae to dispels the severe water pollution by the old technology. Methods: The xylenc is used to extract alkaloids in replace of water, The factors associated with feasibility of the technological process has been established, including the extraction temperature, the amount of base used in the transformation of the organic salt of alkaloids and the powder degree of herba ephedrae. The influence of the extraction time on the rate of extraction is observed and the way to measure the amount of alkaloids in the extractive liquid is established. Result: The new process of extracting alkaloids in herba ephedrae is designed. The rate of extraction is 0. 6 %. Conclusion: The feasibility of the technological process to extract alkaloids in herba ephedrae using the xylenc has been established.