The animal experiment of a new optimised distraction implant |
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Authors: | Bo Shao Yingying Sun Yuan Gao Tao Li Yongfeng Li Yongqiang Zhang Xu Ge Baolin Liu Liang Kong |
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Affiliation: | 1. Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi’ an, 710032, PR China;2. Department of Stomatology, Hainan Branch of PLA General Hospital, Sanya, 572013, PR China;3. Department of Stomatology, PLA 263 Hospital, Beijing, 101149, PR China;4. Department of Stomatology, Second Artillery General Hospital of PLA, Beijing, 100088, PR China |
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Abstract: | Our aim was to evaluate the function of a new optimised distraction implant. Six dogs with alveolar bone defects had a total of 18 distraction, and 6 normal, implants inserted into edentulous mandibular ridges after osteotomy. Five days after insertion the distraction implants were activated at a rate of 1 mm/2 days to achieve a distraction height of 6 mm. Radiographs were taken at 0, 1, 2, and 3 months after distraction. Two dogs were killed after 1, 2, and 3 months, respectively, and 12 distraction implants taken from the different time points were evaluated by microcomputed tomographic (MicroCT) scanning and histological examination. The other 6 distraction, and the 6 normal, implants were compared after osseointegration with a fatigue test. The results showed that all the distraction implants had successfully distracted the bone to the anticipated height. Radiographs showed that the density of the regenerated bone increased steadily during the consolidation period. MicroCT showed that the regenerated bone was comparable with the native bone 3 months after distraction. Both native and regenerated bone had osseointegrated histologically by 1 month and 3 months after distraction. The experiment successfully confirmed the usefulness and feasibility of this new distraction implant, and suggests interesting clinical uses. |
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Keywords: | Distraction implant Distraction osteogenesis Radiographs Micro-computed tomography Histology Animal experiment |
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