| 肝癌肿瘤微环境中非癌细胞成分的研究进展与介入治疗展望 |
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| 引用本文： | 林乐涛,邹英华. 肝癌肿瘤微环境中非癌细胞成分的研究进展与介入治疗展望[J]. 中国介入影像与治疗学, 2017, 14(6): 378-381 |
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| 作者姓名： | 林乐涛 邹英华 |
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| 作者单位： | 北京大学第一医院介入血管外科, 北京 100034,北京大学第一医院介入血管外科, 北京 100034 |
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| 摘 要： | 肝癌肿瘤微环境中的非癌细胞成分,因其基因组的相对稳定性而受到关注。本文从肿瘤微环境的组成及其特点、肝癌肿瘤微环境的组成出发,对肝癌肿瘤微环境中非癌细胞成分的3个研究新的热点(外泌体、趋化因子及无生物活性条件的局部调节)进行综述,并对其在介入治疗方面的应用进行展望。
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| 关 键 词： | 肿瘤微环境 外泌体 趋化因子 局部条件 介入治疗 |
| 收稿时间： | 2017-02-02 |
| 修稿时间： | 2017-03-26 |
Research progresses on non-cancer-cell component of tumor microenvironment in hepatocellular carcinoma and prospect of interventional therapy |
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| LIN Letao and ZOU Yinghua. Research progresses on non-cancer-cell component of tumor microenvironment in hepatocellular carcinoma and prospect of interventional therapy[J]. Chinese Journal of Interventional Imaging and Therapy, 2017, 14(6): 378-381 |
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| Authors: | LIN Letao and ZOU Yinghua |
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| Affiliation: | Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing 100034, China and Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing 100034, China |
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| Abstract: | The non-cancer-cell component of the tumor microenvironment in hepatocellular carcinoma (HCC) has drawn the attention of the researchers because of its relative stability of the genome. The composition and characteristics of the tumor microenvironment and the composition of the tumor microenvironment in hepatocellular carcinoma were introduced in this article. Besides, the recent studies about the non-cancer-cell component of the tumor microenvironment in HCC were reviewed from three aspects:The exosomes, the chemokines and the local conditions without biological activity. The application of non-cancer-cell in interventional treatment in the future was also discussed. |
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| Keywords: | Tumor microenvironment Exosome Chemokine Local condition Interventional therapy |
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