| 番茄红素对大鼠体内抗氧化系统功能的影响 |
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| 引用本文： | 潘洪志,石刚,陈文华,王德才. 番茄红素对大鼠体内抗氧化系统功能的影响[J]. 卫生研究, 2003, 32(5): 441-442 |
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| 作者姓名： | 潘洪志 石刚 陈文华 王德才 |
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| 作者单位： | 1. 哈尔滨医科大学公共卫生学院,哈尔滨,150001
2. 哈尔滨教师体育学院 |
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| 基金项目： | 黑龙江省十五攻关课题 (No .ZB0 2B40 2 - 1 ) |
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| 摘 要： | 目的 观察番茄红素 (lycopene ,LP)对大鼠抗氧化酶系统的影响。方法 大鼠饲喂番茄红素 4周后处死 ,测定血清和肝匀浆的超氧化物歧化酶 (SOD)活性、过氧化氢酶 (CAT)活性、谷胱甘肽过氧化物酶(GSH -Px)活力、总抗氧化能力 (T -AOC)、丙二醛 (MDA)及还原型谷胱甘肽 (GSH)含量。结果 各番茄红素给药组的大鼠血清和肝组织的SOD活性、GSH -Px活力及T -AOC上升 ,MDA含量降低 ,与空白组相比 ,在统计学上差异有显著性 (P <0 0 5 )。结论 番茄红素可以提高大鼠机体的抗氧化能力 ,抑制脂质过氧化
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| 关 键 词： | 番茄红素 抗氧化 大鼠 |
| 文章编号： | 1000-8020(2003)05-0441-02 |
| 修稿时间： | 2002-10-10 |
Effect of lycopene on the function of antioxidative enzyme system in rats |
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| Pan Hongzhi,Shi Gang,Chen Wenhua,Wang Decai Public Health School of Harbin Medical University,Harbin ,China. Effect of lycopene on the function of antioxidative enzyme system in rats[J]. Journal of hygiene research, 2003, 32(5): 441-442 |
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| Authors: | Pan Hongzhi Shi Gang Chen Wenhua Wang Decai Public Health School of Harbin Medical University Harbin China |
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| Affiliation: | Public Health School of Harbin Medical University, Harbin 150001, China. |
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| Abstract: | In order to observe the effect of Lycopene(LP) on antioxidation in rats, the rats were given LP by oral. After 4 weeks the activity of SOD , MDA and GSH-Px,T-AOC,GSH,CAT in serum and liver were measured respectively. The result showed that the activities of SOD,T-AOC and GSH-Px in LP group were increased and the concentrations of MDA were decreased significantly(P<0.05) compared with control group. LP could increase antioxidative effect and reduce lipid peroxidation in Wistar rats. |
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| Keywords: | lycopene antioxidation rat |
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