依那普利和倍他乐克对长期血透病人左心肥大的影响

目的和方法：比较依那普利和倍他乐克对血透病人左心功能及心肌重量的影响。血两 被分为３组，比较１２个月后血压、左心功能及左心肥大的改变。结果：组１（依那普利）和组２（倍他乐克）在治疗后血压有同等程度不下降，而心脏检查示：治疗后，组１舒张末期左这人径９ＬＶＥＤＤ）、左室心肌重量（ＬＶＭ）、左 室心肌重量指数（ＬＶＭＩ）、室间隔厚度（ＩＶＳ）、左室后壁厚度（ＬＶＰＷＤ）、和二尖瓣舒张晚期最大充盈速度（Ａ

Compare the effects of lisinopril and metoprolol on myocardial mass of chronic hemodialysis patients

AIM and METHODS: Compare the effects of lisinopril(LP) and metoprolol(MP) on diastolic function and myocardial mass in chronic hemodialysis patients.Patients were divided into three groups. Alternation of left ventricular function and left ventricular hypertrophy were compared after twelve months' treatment. RESULTS: Both group 1 (LP) and group 2 (MP) had their blood pressure sink to the same degree. But heart examinations showed that after the therapy, left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVESD),left ventricular mass (LVM), LVM corrected for body surface area (LVMI), interventricular septum diameter (IVS), left ventricular posterior wall diameter (LVPWD) and peak velocity of late diastolic filling (A) of group 1 were decreased significantly, while peak velocity of early diastolic filling (E) and ratio of early to late diastolic flow velocity (E/A) were increased significantly. Change of LVMI was in significant positive correlation with Bp-mean. There were not much change in group 2 and the control group. CONCLUSION: The present study showed that ACE-inhibitor had noticiable curative effect on chronic hemodialysis patients, with diastolic function improved and left ventrical hypertrohpy alleviated.